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CAS: | 129453-61-8 | Synonyms: | FASLODEX |
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Molecular Fomular: | C32H47F5O3S | Molecular Weight: | 606.77 |
Density: | 1.201 G/cm3 | Melting Point: | 104-106¡æ |
High Light: | Anti Estrogen Drugs Bodybuilding,anti estrogen bodybuilding |
Faslodex / Fulvestrant Acetate CAS 129453-61-8 Anti Estrogen Anaboli Steroid Powder
Description:
Fulvestrant Acetate (Faslodex, AstraZeneca) is a drug treatment of hormone receptor-positive metastatic breast cancer in postmenopausal women with disease progression following anti-estrogen therapy. It is an estrogen receptor antagonist with no agonist effects, which works by down-regulating the estrogen receptor.
Fulvestrant Acetate is a selective estrogen receptor down-regulator (SERD). Fulvestrant Acetate is indicated for the treatment of hormone receptor positive metastatic breast cancer in postmenopausal women with disease progression following anti-estrogen therapy. The dosing schedule for fulvestrant Acetate remains under investigation in an attempt to optimize its effectiveness.
Fulvestrant Acetate provided effective second-line therapy in this setting for postmenopausal women who had relapsed or progressed after previous endocrine therapy.
Applications:
Many breast cancers are stimulated to grow by the female sex hormones oestrogen and progesterone. These breast cancers are called hormone sensitive or hormone receptor positive. Drugs that block the effects of these hormones can slow or stop the growth of the breast cancer cells. Fulvestrante stops oestrogen getting to the cancer cells by blocking oestrogen receptors and reducing the number of receptors the cancer cell has.
Fulvestrante (Faslodex, AstraZeneca) is a drug treatment of hormone receptor-positive metastatic breast cancer in postmenopausal women with disease progression following anti-estrogen therapy. It is an estrogen receptor antagonist with no agonist effects, which works by down-regulating the estrogen receptor.
Fulvestrante is a selective estrogen receptor down-regulator (SERD). Fulvestrante is indicated for the treatment of hormone receptor positive metastatic breast cancer in postmenopausal women with disease progression following anti-estrogen therapy. The dosing schedule for fulvestrante remains under investigation in an attempt to optimize its effectiveness.
Fulvestrante provided effective second-line therapy in this setting for postmenopausal women who had relapsed or progressed after previous endocrine therapy.
In particular 4 clinical trials in this setting did show similar efficacy to the other hormonal agents (aromatase inhibitors ) with good tolerability profile. Fulvestrante had a lower incidence of joint disorders.
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