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Intermediate Pharmaceutical Products,
Natural Plant Extract
CAS 63-05-8 High Quality Androstenedione Steroids intermediate Factory Supply
Androstenedione is a steroid hormone which is used for pharmaceutical, and is the common precursor of male and female sex hormones. Some androstenedione is also secreted into the plasma, and may be converted in peripheral tissues to testosterone and estrogens.
Androstenedione can be synthesized in one of two ways. The primary pathway involves conversion of 17-hydroxypregnenolone to dehydroepiandrosterone by way of 17,20-lyase, with subsequent conversion ofdehydroepiandrosterone to androstenedione via the enzyme 3-hydroxysteroid dehydrogenase. The secondary pathway involves conversion of 17-hydroxyprogesterone, most often a precursor to cortisol, to androstenedione directly by way of 17,20-lyase. Thus, 17,20-lyase is required for the synthesis of androstenedione, whether immediately or one step removed.
The production of adrenal androstenedione is governed by ACTH, whereas production of gonadal androstenedione is under control by gonadotropins. In premenopausal women, the adrenal glands and ovaries each produce about half of the total androstenedione(about 3 mg/day). After menopause, androstenedione production is about halved, due primarily to the reduction of the steroid secreted by the ovary. Nevertheless, androstenedione is the principal steroid produced by the postmenopausal ovary.
|Synonyms||4 - androstenedione; 4 - male (steroid)-ene -3,17 - dione;|
|Specification||99% Heavy 10PPM Rotation +193 ¡ã - +202 ¡ã Loss on drying 0.5% impurity 1% steroid hormone|
|Packing||foil bag or tin.|
|Appearance||near white crystalline powder, soluble in ethanol, insoluble in water|
|Storage||Shading , Confined Preservation|
|Usage||Simplified hormone drugs, from the testis or urine extracted with the role of a male hormone steroids, norethisterone, testosterone propionate in the middle|
Body, is widely used in small rheumatoid arthritis, diuretic, and a variety of contraceptive to control infectious inflammation.
4-Androstenedione is further converted to either testosterone or estrogen.
In males, conversion of androstenedione to testosterone requires the enzyme 17β-hydroxysteroid dehydrogenase.
In females, androstenedione is released into the blood by theca cells. Conversion of androstenedione to estrogen (e.g., estrone and estradiol) requires the enzyme aromatase. Androstenedione is a substrate for estrogen production in granulosa cells which produce aromatase. Thus, theca cells and granulosa cells work together to form estrogens.
Used for simplified hormone drugs, from the testis or urine extracted with the role of a male hormone steroid, norethisterone, testosterone propionate in the middle body, is widely used in small rheumatoid arthritis, diuretic, and a variety of contraceptive to control infectious inflammation.
Androstenedione is used to increase the production of the hormone testosterone to enhance athletic performance, increase energy, keep red blood cells healthy, enhance recovery and growth from exercise, and increase sexual desire and performance.
Androstenedione gained popularity as the supplement used by the baseball homerun hitter Mark McGwire and other professional sports players. In January 2005 legislation went into effect in the United States called the Anabolic Steroid Control Act of 2004. This reclassifies androstenedione from a dietary supplement to an anabolic steroid, which is a schedule III controlled substance.
It is used by the body to make testosterone and estrogen.It Increases Lean Muscle Mass, Muscle Recovery, Strength & Endurance,Protein Synthesis, Nitrogen Retention and Libido (Sex Drive).
Range from 5 to over 50mg per day in the morning or 60 minutes before working out.
Experts suggest the best way to take andro is by cycling it. The proper cycle is six weeks of taking it followed by two weeks off.
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