Setipiprant Pharmaceutical Raw Materials CAS 866460-33-5 For Acne

Setipiprant Pharmaceutical Raw Materials CAS 866460-33-5 For Acne Best Quality Setipiprant

Quick Detail;

Product name: Setipiprant

CAS: 866460-33-5

Standard: enterprise standard

Presence of:
synthetic: synthetic

Level: medical

Content: 98%

Appearance: white powder

Packing: 100G/ aluminum foil bag

Category: chemical raw materials

Industry: chemical raw materials

Field: anti - caking agent

what is the Setipiprant:

Setipiprant binds to the DP2 receptor with a dissociation constant of 6 nM, representing potent antagonism of the receptor.The DP2 receptor, also called the CRTh2 receptor, is a G-protein-coupled receptor that is expressed on certain inflammatory cells, such as eosinophils, basophils, and certain lymphocytes.For its mechanism of action in the treatment of allergic conditions, setipiprant's DP2 antagonism prevents the action of prostaglandin D2 on these receptors.

The DP2 receptor mediates the activation of type 2 helper T (Th2) cells, eosinophils, and basophils in the lungs, which are white blood cells implicated in producing the inflammatory response the characterizes allergic conditions.Activation of DP2 on Th2 cells by PGD2 induces the secretion of inflammatory cytokines, which cause an increase of eosinophils in the blood, remodeling of lung tissue, and hypersensitivity of lung tissue to allergens.

Setipiprant does not antagonize the thromboxane receptor (TP).The bronchoconstricting properties of PGD2 are not inhibited by setipiprant, since these are mediated by the TP receptor.As a point of contrast, ramatroban is a selective TP antagonist and DP2 receptor antagonist.

Product advantages:

About powder quality

Our product is powders and liquids, the purity of the powder is 99%, so many customers are satisfied with our quality, they often buy our powders. at the some times, They will sell liquid, yes, brother, they make a lot of money.

About liquid quality

Clarity of the liquid is very high, there are many customers think the powder is very complex, so they can directly buy our liquid effect is very good! of course,you buy our powder, we can tell you the method of making the liquid If you buy a liquid, we will tell you how to filter

About Safe transportation

Our mode of transport is taken according to each country's situation is different transportation, while our packaging, according to the latest customs situation, constantly updated, improved our packaging, we guarantee that you receive it within 4-7 to your product.