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Chemical Name: | Flibanserin CAS 147359-76-0 | Customized: | Non-Customized |
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Purity: | >98% | Apprarance: | White Crystalline Powder |
Certification: | ISO 9001 | HS Code: | 3001200090 |
High Light: | natural growth hormone supplements,peptide hormones drugs |
Healthy Medicine Powder Flibanserin CAS 147359-76-0 for Female Weight Loss
Description:
Flibanserin, sold under the trade name Addyi, is a medication approved for the treatment of pre-menopausal women with hypoactive sexual desire disorder (HSDD). The medication increases the number of satisfying sexual events per month by about one half over placebo from a starting point of about two to three. The certainty of the estimate is low. The side effects of dizziness, sleepiness, and nausea occur about three to four times more often.
HSDD was recognized as a distinct sexual function disorder for more than 30 years, but was removed from the Diagnostic and Statistical Manual of Mental Disorders in 2013, and replaced with a new diagnosis called female sexual interest/arousal disorder (FSIAD).
COA:
Items | Specification |
pH | 3.5-4.5 |
Identification | 1, red to dark purple color appears |
with(III)iron chloride | |
2, light red precipitate formed with reinecke salt TS | |
3, UV spectrum meet the reference | |
4, solution (1%) responds to the qualitative test for chloride | |
Melting point | 139-143 celcius degree |
Clarity and color of solution | clear and colorless |
Sulfate | 0.048%max |
Heavy metals | 10ppm max |
As | 2ppm max |
Organic acid(0.1M NaOH) | 0.54ml max |
Loss on drying | 0.5% max |
Residue on ignition | 0.1%max |
Residual organic Solvents (GC) | Xylol 0.217%max |
Isopropanol 0.5%max | |
Related substances(HPLC) | Total impurity 1.5%max |
Single impurity0.5%max | |
Free P-chloro phenoxy acetic 0.5%max | |
Count of bacteria | bacillus 1000/1g max |
Mildew 100/1g max | |
Microzyme 100/1g max | |
Assay(C12H16CINO3.HCl,on dry basis) | 98%min |
Usage:
Flibanserin is used for hypoactive sexual desire disorder among women. Those receiving flibanserin report a 0.5 increase compared to placebo in the number of times they had “satisfying sexual events”.[4] In those on flibanserin it rose from 2.8 to 4.5 times a month while women receiving placebo reported also an increase of “satisfying sexual events” from 2.7 to 3.7 times a month. The onset of the flibanserin effect was seen from the first timepoint measured after 4 weeks of treatment and maintained throughout the treatment period.
The effectiveness of flibanserin was evaluated in three phase 3 clinical trials. Each of the three trials had two co-primary endpoints, one for satisfying sexual events (SSEs) and the other for sexual desire. Each of the 3 trials also had a secondary endpoint that measured distress related to sexual desire. All three trials showed that flibanserin produced an increase in the number of SSEs and reduced distress related to sexual desire. The first two trials used an electronic diary to measure sexual desire, and did not find an increase.
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