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anti estrogen drugs for men,
Anti Estrogen Drugs Bodybuilding
Safe Shipping CAS 89778-27-8 Anti Estrogen Steroids Toremifene Citrate
Fareston (Toremifene Citrate, known in bodybuilding circles as "torem") is a selective estrogen receptor modulator (SERM) derived from triphenylethylene. It is FDA approved for breast cancer treatment, and has possible medical uses for prostate cancer. Bodybuilders will use this drug to combat gynecomastia (bitch tits), but it's still very new to the scene and has some drawbacks.
Toremifene Citrate exerts its effects by antagonizing the estrogen receptor in some tissues, and agonizing it in others. In this way, certain estrogenic pathways are activated and others are blockaded. It seems to exert estrogenic effects on blood lipids, reducing LDL and total cholesterol, as well as estrogenic effects on bone, improving density. It would also appear to exert anti-estrogenic effects in breast tissue, displacing the traditional effects of estrogen, effectively helping prevent breast cancer in postmenopausal women.
|Product Name||Toremifene Citrate|
FC 1157a; Fareston; NK 622; NSC 613680
|Melting Point||158-164 ºC|
|Boiling Point||535.1 ºC at 760 mmHg|
|Packing||foil bag or tin.|
|Appearance||White or almost white powder|
|Storage||Shading , confined preservation|
|Usage||Anti-estrogen (fertility induction content), the thing in the dysfunctional uterine bleeding, polycystic ovary, menstrual disorders and drug cause amenorrhoea and gynecological diseases.|
|Molecular Fomular||C26H28ClNO C6H8O7|
Toremifene is used in postmenopausal women to treat breast cancer that has spread to other parts of the body (metastatic breast cancer). It is usually used to treat cancerthat needs estrogen, a female hormone, in order to grow (estrogen-receptor positive). Toremifene is a nonsteroidal antiestrogen that blocks the effects of estrogen in thebreast tissue, thereby slowing or stopping the growth of cancer.
It has already been covered that Toremifene is a SERM, and serves to block Estrogen at various receptor sites in certain tissues within the body (breast tissue in particular). As a layman explanation, Toremifene pretends to be a 'fake' Estrogen that occupies Estrogen receptors within breast tissue. With these receptors occupied by Toremifene, real Estrogen cannot perform their jobs there. Toremifene does not reduce total blood plasma levels of Estrogen. In addition to being antagonistic to Estrogen receptors in breast tissue, it is also antagonistic to Estrogen at the hypothalamus gland (this essentially 'tricks' the hypothalamus into thinking there is little or no circulating Estrogen levels in the body, causing it to increase its manufacture of Testosterone so that it can utilize aromatization to restore these levels.
For bodybuilding purposes, a dose of 40-60mgs per day seems to be a good starting point. If the user is trying to fight existing gynecomastia (bitch tits), they may choose to double the dose and add an aromatase inhibitor like Aromasin with it. For PCT, some users will kick-start with 100-120mgs per day and then lower to 40-60mgs per day for 4-6 weeks.
Post Cycle Therapy (PCT):
When a steroid user runs a cycle their HPTA becomes suppressed; as a result, their bodies LH and FSH drop to almost zero (0) and their body stops producing testosterone. Their testicles typically will shrink as the body realizes there are too many hormones present and it's not necessary to produce more. So, when you come off a cycle it's important to run a PCT (post cycle therapy) to help recover the body's HPTA.
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|Description||White or Almost White Crystalline Powder||white powder|
|Loss On Drying||1.0%max||0.28%|
|Organic Volatile Impurities||meets the requirement.||Conforms|
|Related Substances||meets the requirement.||Conforms|
|Residual Solvents||meets the requirement.||Conforms|
|Particle Size||100% ≤ 20 microns||Conforms|
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