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Cardarine GW501516 Sarms Steroids,
317318 70 0 Sarms Steroids
CAS 317318-70-0 Cardarine GW501516 Sarms Steroids for Muscle Endurance
What is GW501516?
GW-501516, better known as Cardarine, is a unique medication officially classified as a PPAR receptor agonist (PPAR-RA). Research for this medication began in 1992 in a conjoined effort between GlaxoSmithKline (GSK) and Ligand Pharmaceuticals. Research into this product was set forth in an effort to provide treatment for various cardiovascular diseases, as well as diabetes, obesity and other conditions. It was soon discovered that the PPAR-RA was highly effective at enhancing endurance, but it was also shown to carry a high potential cost. It was discovered that Cardarine increased the chances of cancer significantly, and as a result, GSK dropped all further research. However, the studies that produced cancerous results used doses of Cardarine that were 500 to even 1000 times the amount that a human being would take. If cancer is a risk with standard dosing is unknown.
Cardarine Functions and Traits
Cardarine (GW-501516) binds to the PPAR receptor, specifically a group of nuclear receptors (sensors that detect thyroid and steroidal hormones in the body) that initiates the PGC-1a enzyme. This action leads to gene expression, specifically genes that revolve around energy expenditure.
Studies involving GW-501516 have shown to increase the metabolism of fatty acids in rats. It was also shown in the same studies to reduce the odds of obesity despite poor eating habits as well as prevent Type-2 diabetes. Cardarine was also shown to increase HDL (good cholesterol) and decrease LDL (bad cholesterol) in a study using monkeys. The effects seemed to hold true with or without exercise.
The Effects of Cardarine:
The effects of Cardarine are fairly significant and may be a welcomed addition to the stack for a performance athlete. Increased endurance may be the PPAR-RA’s most incredible attribute. Those who use the medication will find they do not tire out as easily and can train harder and longer. The cardiovascular endurance that comes with Cardarine is so strong it has been shown to do away with the cardio issues that surround the popular anabolic steroid Trenbolone. Many who use Trenbolone report breathing becomes a bit more difficult and that cardio becomes a more arduous task. Cardarine seems to negate this negative effect when using Tren.
The effects of Cardarine also help tremendously with fat loss. If nothing else, you’re able to perform your cardio more intensely and longer. Further, it doesn’t carry any catabolic effect that is associated with many thermogenics or fat burners, meaning muscle loss due to use is of no concern. More importantly, GW-501516 has been shown to increase nutrient efficiency. Simply put, you make better use of the nutrients you’re consuming. Those who use the compound will find increased levels of glucose uptake and fat stores reduced.
Side Effects of Cardarine
The known side effects of Cardarine primarily surround increasing the chances of cancer; however, it’s not quite that cut and dry. Studies that showed increased cancer rates in rats used doses of the PPAR-RA far above and beyond what any human would take. Further, additional studies have shown GW-501516 decreased existing cancerous tumors and in effect cured the existing cancer. The truth behind the relationship with this drug and cancer is unknown at this time. Because there is a potential relationship between the medication and cancer, we may never know the truth as it’s unlikely any major pharmacy group will undertake any additional study.
Estrogenic: There are no estrogenic side effects associated with GW-501516. Water retention, bloating, gynecomastia and high blood pressure associated with water retention is not possible as there is no conversion of testosterone to estrogen.
Androgenic: The side effects of Cardarine do not include any of an androgenic nature. Hair loss, acne and virilization symptoms in women are not possible with this medication.
Cardiovascular: There are no negative side effects of Cardarine associated with cardiovascular health; in fact, lipids may improve. In a study done by the Journal of Cardiology, GW-501516 was stated to possibly reduce the risk of heart attack.
Testosterone Suppression: GW-501516 will not suppress natural testosterone production. Post Cycle Therapy (PCT) is not needed when using this PPAR-RA.
Hepatotoxicity: Cardarine is not toxic to the liver.
GW-501516 is taken orally. The most common dosing range for this PPAR-RA is 10-15mg per day for 8 weeks. However, some reports state the medication needs to be used for 12 weeks for optimal results, with 20mg per day being well tolerated by most individuals.
Availability of Cardarine
GW-501516 is available through some research chemical companies although not one of the more common products carried. You may also find some anabolic steroid suppliers that carry it; however, the latter will not be a legal purchase. Research chemical companies exist due to a gray area of the law, and while purchasing is legal, it is only legal for research purposes.
Based on its positive attributes, Cardarine may be one of the single best products an athlete could buy. However, although not an anabolic steroid, numerous sporting bodies have already banned it and it will show up in sports doping tests. But when it comes to the benefits, endurance and enhancing nutrient efficiency are two benefits that are hard to beat. It’s hard to beat this into the head of many athletes, recovery, endurance and food itself are the three most important factors associated with making gains or improving performance, and Cardarine does just that.
Although the benefits of Cardarine are undeniable, we are still left with the glaring possibility of use-induced cancer. Regardless of how much muscle you carry or how low your body fat is, cancer is going to ruin the physique you’ve built, not to mention your life. The odds of cancer, from looking at some of the studies that were done they do appear to be somewhat flawed, while others scream warning. It is truly hard to say what would happen if you were to try this drug, but there does appear to be a legitimate risk, and enough of one to cause a very large pharmaceutical giant to completely give up on what could have been a highly profitable drug had the cancer scare not existed.
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