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| Assay: | 99% Min | CAS: | 330784-47-9 |
|---|---|---|---|
| Molecular Formula: | C23H26ClN7O3 | Molecular Weight: | 483.9506 |
| Character: | White To Off-White Cyrstalline Solid | Usage: | Used For The Treatment Of Erectile Dysfunction |
| High Light: | anti estrogen drugs bodybuilding,male enhancement powder |
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Sex Enhancer Steroids Hormone Avanafil for Male Sexual Dysfunction CAS:330784-47-9
Description:
Avanafil is a PDE5 inhibitor approved for erectile dysfunction by FDA on April 27, 2012 and by EMA on June 21, 2013. Avanafil acts by inhibiting a specific phosphodiesterase type 5 enzyme which is found in various body tissues, but primarily in the corpus cavernosum penis, as well as the retina. Other similar drugs are tadalafil and vardenafil. The advantage of avanafil is that it has very fast onset of action compared with other PDE5 inhibitors. It is absorbed quickly, reaching a maximum concentration in about 3045 minutes.
Usage:
It is a development of the phosphodiesterase type 5 inhibitors, for the treatment of male sexual dysfunction, at present in the America, EU and Japan have completed phase II clinical trials, phase III clinical trials will start. The product is composed of Japanese Tanabe Pharma Company and VIVUS company development. In addition to oral dosage forms, VIVUS company is also developing Avanafil urethral administration, for not responding to oral dosage forms of patients.
Dosage :
For most individuals, the recommended starting dose of avanafil is 100 mg per day taken about 30 minutes before sexual activity. Depending on the adequacy of the response or side effects, the dose may be increased to 200 mg or decreased to 50 mg a day. Individuals who are taking medications that moderately increase the blood levels of avanafil should not exceed a total dose of 50 mg in 24 hours.
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