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|Chemical Name:||Orlistat||CAS:||96829-58-260 Orlistat|
|Usage:||Treat Obesity||Assay:||98% Min.|
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Pharmaceutical Raw Weight Loss Ingredient Orlistat Factory Supply 96829-58-260
Orlistat is a drug designed to treat obesity. It is marketed as a prescription drug under the trade name Xenical by Roche in most countries, and is sold over-the-counter as Alli in the United Kingdom and the United States. Its primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake. It is intended for use in conjunction with a healthcare provider-supervised reduced-calorie diet.
Orlistat is the saturated derivative of lipstatin, a potent natural inhibitor of pancreatic lipases isolated from the bacterium Streptomyces toxytricini.However, due to its relative simplicity and stability, orlistat was chosen over lipstatin for development as an anti-obesity drug.
The effectiveness of orlistat in promoting weight loss is definite but modest. Pooled data from clinical trials suggest that people given orlistat in addition to lifestyle modifications, such as diet and exercise, lose about 2–3 kilograms (4.4–6.6 lb) more than those not taking the drug over the course of a year. Orlistat also modestly reduces blood pressure and appears to prevent the onset of type 2 diabetes, whether from the weight loss itself or to other effects. In a large randomized controlled trial, orlistat was found to reduce the incidence of diabetes by nearly 40% in obese people.
Orlistat blocks some of the fat that you eat, keeping it from being absorbed by your body.
Orlistat is used to aid in weight loss, or to help reduce the risk of regaining weight already lost. This medicine must be used together with a reduced-calorie diet. Orlistat is for use only in adults.
Orlistat is used for the treatment of obesity. The amount of weight loss achieved with orlistat varies.
Alli (orlistat) is an over-the-counter medication used to help people lose weight. Studies have shown that Alli can help people lose more weight than dieting alone. The weight loss drug is intended for overweight adults ages 18 and older who also follow a reduced-calorie, low-fat diet.
A stronger dose of the same active ingredient in Alli is available by prescription and is sold under the brand name Xenical. Xenical may also be recommended after weight loss surgery to help patients keep off the lost pounds.
How Does Alli Work?
Alli belongs to a class of drugs called lipase inhibitors. It blocks the intestines from absorbing about 25% of the fat that you eat. Fats that aren’t absorbed leave your body through bowel movements. Some data suggest that Alli helps reduce the amount of a particularly dangerous type of belly fat called visceral fat, which has been linked to type 2 diabetes, high blood pressure, heart disease, and stroke.
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|Appearance||white or almost white crystalline powder,smell less|
|Identification||The result of HPLC is consisitent to the reference one. The result of IR is consisitent to the reference one.|
|Related Substances||≤ 0.5%|
|Total impurity||≤ 1.0%|
|Single impurity||≤ 0.1%|
|Residual on Ignition||≤0.1%|
|Heavy Metal||≤ 20ppm|
|Purity||≤ 99.0% ~ 99.9%
orlistat bula em portugues
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