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anti estrogen drugs for men,
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Exemestane Anti Estrogen Steroids for Bodybuilding CAS 107868-30-4
In women who have had their menopause, oestrogen is mainly produced by changing androgens (sex hormones produced by the adrenal glands) into oestrogens. This process is called aromatisation and happens mainly in the fatty tissues, muscle and the skin. It needs a particular enzyme called aromatase.
Exemestane is an oral steroidal aromatase inhibitor that is used in ER-positive breast cancer in addition to surgery and/or radiation in post-menopausal women. Exemestane is a drug used in the treatment of breast cancer in women who have gone throughmenopause. It may be used in women for whom adjuvant tamoxifen therapy is not working or in women with advanced breast cancer that is not responding to treatment. This drug is available by prescription only and women must be supervised by a doctor while they take it. It is sold under the brand name Aromasin and some pharmacies may require advance notice to stock it because it is not a frequently used medication in some areas.
Aromasin ; Exemestan; Exemestance, Exalamide, ExeMestine
|Packing||foil bag or tin.|
|Appearance||White or almost white powder|
|Storage||Shading , confined preservation|
Exemestane is a steroidal Aromatase Inhibitor (AI) that is most commonly known as Aromasin.
Aromasin is officially classified as a steroidal suicide Aromatase Inhibitor, and carries the ability to inhibit the aromatase enzyme, which is responsible for the production or conversion of testosterone to estrogen. Aromasin has the ability to block aromatization, which in turn inhibits the production of estrogen, and thereby lowers the body's serum estrogen levels. This will prove useful to breast cancer patients as breast cancer often feeds off the estrogen hormone. It will also prove useful to the anabolic steroid user.
Many anabolic steroids have the ability to increase estrogen levels due to the aromatase process, specifically the conversion of testosterone to estrogen. This can lead to gynecomastia and water retention. Excess water retention can also promote high blood pressure when it becomes severe. Steroids that do not carry a strong estrogenic nature can also cause these effects, most notably gynecomastia if they carry a progestin nature. A prime example would be Nandrolone, which while it aromatizes only does so at 20% the rate of testosterone. However, it also carries a strong progestin nature, and progesterone has been well noted for carrying the ability to stimulate the estrogenic mechanism in the mammary tissue. By administering Aromasin during the use of anabolic steroids, this will inhibit the aromatase process, lower estrogen levels and protect the individual from estrogenic side effects. How effective is Aromasin? The product claims on average to have the ability to lower serum estrogen levels by 85%.
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|Description||: White Crystalline Powder||White Powder|
|Assay(by HPLC)||: 98.0~102.0%||98.64%|
|Melting Point||: 191~195°C||193.5~195.0°C|
|Loss On Drying||: 0.5%max||0.19%|
|Specific Rotation||: +288°~ +298°||+290.2°|
|Residue On Ignition||: 0.1%max||0.03%|
|Related Substances||: Total:1.5%max||<1.3%|
|Residue Solvents||: 0.2%max||0.10%|
|Heavy Metals||: 20PPm max||<10PPm|
|Conclusion||The specification conform with enterprise standard.|
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|4||Toremifene citrate||CAS: 89778-27-8|
|6||Anastrozole (Arimidex)||CAS: 120511-73-1|
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