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5630-53-5 High Purity Estrogen Hormone Steroid Powder Tibolone Acetate Livial

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5630-53-5 High Purity Estrogen Hormone Steroid Powder Tibolone Acetate Livial

5630-53-5 High Purity Estrogen Hormone Steroid Powder Tibolone Acetate Livial
5630-53-5 High Purity Estrogen Hormone Steroid Powder Tibolone Acetate Livial 5630-53-5 High Purity Estrogen Hormone Steroid Powder Tibolone Acetate Livial

Large Image :  5630-53-5 High Purity Estrogen Hormone Steroid Powder Tibolone Acetate Livial Get Best Price

Product Details:
Place of Origin: China
Brand Name: yuancheng
Certification: GMP
Model Number: 5630-53-5
Payment & Shipping Terms:
Minimum Order Quantity: 0g
Price: negotiation
Packaging Details: foil bag or tin.
Delivery Time: 4-7days
Payment Terms: Bank Transfer, Western Union, MoneyGram,Bitcoin
Supply Ability: 100kg/week
Detailed Product Description
Synonyms: TIBOLONE; LIVIELLA; LIVIAL CAS: 5630-53-5
EINECS: 227-069-1 Assay: 99% Min
Packing: 1kg/foil Bag Character: White Powder
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5630-53-5 High Purity Estrogen Hormone Steroid Powder Tibolone Acetate Livial

 

Description:

 

 

Tibolone Livial/Liviella is used mainly for treatment of endometriosis, as well as hormone replacement

 

therapy in post-menopausal women. Tibolone is a synthetic steroid hormone drug, which is fairly non-

 

selective in its binding profile, acting as an agonist mainly at estrogen receptors, with a preference for ER

 

alpha. Tibolone has similar or greater efficacy compared to older hormone replacement drugs, but shares

 

a similar side effect profile. It has also been investigated as a possible treatment for female sexual

 

dysfunction.

Tibolone is a synthetic hormone-type drug which is used mainly for hormone replacement therapy in post-

 

menopausal women. It is a synthetic steroid that has the same activity as the female sex hormones

 

estrogen and progesterone and the androgen testosterone. Tibolone helps restore hormonal balance in

 

the body.

When estrogen levels are low tissues can slowly degenerate, as is experienced during menopause. In

 

addition, low levels of estrogen can cause distressing symptoms such as hot flushes, night sweats, mood

 

swings, reduced sex drive and vaginal dryness. Tibolone is broken down into three compounds which act

 

in a similar way to the natural estrogen and progesterone found in the body. It restores plasma endorphin

 

level in post-menopausal women and acts centrally to affect the thermo-regulatory system.

 

 

Applications:

 

 

In itself Tibolone has no biological activity; the effects are produced mainly by the results of the activity of

 

its metabolites on various tissues. After administration, Tibolone is quickly metabolized into 3¦Á-

 

hydroxytibolone and 3--hydroxytibolone compounds, which are also present in an inactive, sulfated form.

 

A third compound, the ¦¤4- isomer is formed from Tibolone directly or from the 3h hydroxymetabolite.


Tibolone has estrogenic effects on bone and vaginal tissue. The ¦¤4-isomer functions as a progestogen in

 

endometrial tissue, whereas in the brain and liver it has androgenic effects.In breast tissue, Tibolone acts

 

by strongly inhibiting sulfate activity and weak inhibition of 17¦Á-hydroxysteroid dehydrogenase activity,

 

which results in blocking the conversion of estrone sulfate to E2.


Tibolone Contraindications;Tibolone is contraindicated in patients with the following conditions:,Women

 

with hormone treated tumors,Undiagnosed vaginal bleeding,Pregnancy/lactation,Liver and/or cardiac

 

disease,Tibolone Adverse Drug Effects,Depression,Diarrhea, constipation, nausea, vomiting or abdominal

 

pain,Visual disturbances,Alteration in results of liver function tests,Excessive fluid retention in the body

 

tissues resulting in swelling (edema),weight changes, vaginal bleeding, pain in the muscles and joints,

 

rashes or itching,Seborrhoeic dermatitis,Headaches, dizziness, growth of facial hair


Tibolone interacts with:Rifampicin,Anti-epileptics such as phenytoin, primidone, Phenobarbitone

 

 

   
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5630-53-5 High Purity Estrogen Hormone Steroid Powder Tibolone Acetate Livial 0

 

 

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